![]() In summary, AFL and HF often coexist but are understudied, with no randomized trial data to inform care. When systolic dysfunction was tachycardia‐mediated, catheter ablation demonstrated LVEF normalization in up to 88%, as well as reduced cardiovascular mortality. There was significant variation in treatments studied, including the proportion that underwent ablation. No studies reported the predictors, phenotype, and prognostic implications of AFL in HF. However, the phenotype of HF was never defined by left ventricular ejection fraction (LVEF). ![]() The prevalence of HF in AFL ranged from 6% to 56%. Most cohorts enrolled patients with AF/AFL as interchangeable diagnoses, or highly selected patients with tachycardia‐induced cardiomyopathy. No study described the incidence or prevalence of AFL in unselected patients with HF. A systematic literature review of PubMed/Medline and EMBASE yielded 65 studies for inclusion and qualitative synthesis. ![]() ![]() We reviewed the incidence, prevalence, and predictors of HF in AFL and vice versa, and the outcomes of treatment of AFL in HF. While the interplay between heart failure (HF) and atrial fibrillation (AF) has been extensively studied, little is known regarding HF and atrial flutter (AFL), which may be managed differently. ![]()
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